06 Jan 2019

Dr. Jacknin interviewed for Women in Weed for Centennial Issue

I was happy to be interviewed by Elana Frankel, the editor of the prestigious Women In Weed Magazine:

“Smart Medicine for Your Skin

 The title of Dr. Jeanette Jacknin’s book sparked her understanding of CBD 15 years after it was written. 

In 2001, the book defined integrative dermatology and discussed conventional and holistic treatments for 33 skin conditions. Her belief in combining conventional dermatology with more holistic options as an alternative treatment approach has gained traction over the years. This includes treating the whole person, taking into account psychological and social factors, rather than just physical symptoms, including factors that precede, trigger or exacerbate a condition as well as diet, nutrition and herbal remedies. So, in 2016, when Jacknin tore cartilage in her ankle and a friend suggested CBD for relief instead of traditional pharmaceuticals, it was her medical background and understanding of the confines of current healthcare that led her to study the skin science behind cannabinoids.

CBD, science and skin care

“Hemp oil has great benefits,” says Jacknin. “Even with small amounts of CBD, it is a rich source of omega 3 and 6 fatty acids found in nature as well as vitamins A, B,C,D, and E. Hemp molecules are small and penetrate the skin better than other type of creams and have moisturizing and nutritional properties.” 

So how does it work? The skin has its own endocannabinoid system (“Which is really quite amazing,” notes Jacknin.), helping to regulate the production of various hormones and proteins, including cytokines, which are involved in the immune response, and Caterina-2014 cannabinoid lipids, which regulate sensory, homeostatic and skin inflammation.

Human tissues have at least two types of cannabinoid receptors. CB1 receptors mediate the inhibition of neurotransmitter release (involved with euphoria  found mainly in the brain, but also in the skin), while CB2s modulate cytokine release (usually involved with the anti‐inflammatory qualities mainly found in skin).  A receptor can recognize and bind with molecules, including interactions with phytocannabinoids from cannabis (CBD and THC). The binding affinity of particular cannabinoids to certain types of receptors within the endocannabinoid system have implications in epidermal differentiation (acne and inflammation) and skin development (aging and new cell growth).

 Now what?

There are studies documenting the treatment of acne, eczema, psoriasis and anti-aging but much more is needed. “Expect more in the United States next year,” notes Jacknin. In the meantime, as CBD skincare lines and spa therapies pop up, here are her recommendations.

  1. Look at ingredients. A long list of unpronounceable names is a red flag. If hemp/cbd oil is listed towards the bottom, there is probably hardly any in there. Check the milligram number.
  2. Patch test products before using on the back of your hand or on feet. 
  3. Essential oils are sometimes mixed in to product, so if you have sensitive skin try unscented and be mindful of allergic reactions.
  4. For massage and pain relief, CBD massage oils are a great start but a transdermal product (like a patch) can get under the skin and straight to the muscle. Just be mindful of the adhesive…cheap adhesive can cause a skin reaction.”