18 Jan 2018

Over 130 Cannabinoids? Amazing!

There are now about 130 cannabinoids which have been discovered!  Amazing! CBD is only one of many, but it is the predominant cannabinoid that we have discovered as of today. We are at the forefront of a whole new science, biochemistry, and industry and dermatology has it’s part too!


18 Jan 2018

CBD from Hemp versus Marijuana

CBD or Cannabidiol extracts, which are produced directly from  marijuana flowers, are up to 15 percent CBD (or 150,000 ppm).

CBD extracts can be produced indirectly from hemp manufacture as a by-product of the flowers and leaves that are mixed in with the stalks during hemp stalk processing for fiber. This has been done mostly in Europe and 30 other countries and imported into the US until recently, as it was illegal to cultivate hemp in the US until the 2014 Farm Bill.. Now many states have voted to make hemp cultivation legal for research and industrial production

So, Currently CBD from hemp plants are usually only 25 parts per million (so 25ppm vs. 150,000 ppm CBD from cannabis flowers).

18 Jan 2018

Hemp oil in the Beauty Industry..”New” Again After Thousands of Years.

 While it seems like “cannabis beauty” is a sudden trend, it’s nothing new, with Eastern cultures including China using these effective ingredients for thousands of years. Hemp oil has trace levels of THC  and is heavy in omega fatty acids, which are essential for moisturizing dull skin. Fatty acids in hemp oil also help regenerate the skin’s protective outer layer, leaving it smoother and younger looking. Cannabis creams cannot get you high. They aren’t designed to penetrate the skin or enter the bloodstream. Besides CBD, a cannabinoid, hemp oil contains vitamins C and E to help protect hair from broken or split ends and protect skin and hair against damage from the sun. They also keep free radicals from damaging collagen and elastin, which, as you know, gives skin its tight, youthful appearance.  B complex vitamins found in hemp are part of the construction process of skin, hair, and nails. Vitamins A and D in hemp oil help with healthy looking skin, as they are responsible for skin repair.  Additionally, vitamin A is widely accepted as important for skin cell growth, inhibiting oil production, and promoting skin cell differentiation

15 Oct 2017

Hawaii and 26 other states list medicinal cannabinoids as approved treatment for vets with PTSD.

The following info comes from an article in “Hawaii, Health, and Medicine” in August 2017:

Complementary and Alternative Medicine (CAMO) on Oahu is currently educating Hawaii’s veterans on how to best cope with post-traumatic stress disorder (PTSD) with the help of medicinal cannabis.

Paring adaptive sports activities with medicinal cannabis, CAMO’s services provide disabled veterans and their families a sense of optimism and hope. Though focusing primarily on military veterans, CAMO rejects no one.

Based on the island of Oahu, CAMO provides a modern holistic approach to helping today’s veterans who struggle to overcome mental health issues. A common ailment, approximately eight million adults suffer from PTSD annually. According to the Department of Veterans Affairs:

  •      About 7 or 8 out of every 100 people (or 7-8% of the population) will have PTSD at some point in their lives.
  •      About 8 million adults have PTSD during a given year.
  •      About 10 of every 100 women (or 10%) develop PTSD sometime in their lives compared with about 4 of every 100 men (or 4%).

Does your state recognize cannabis as a treatment for PTSD?

Hawaii is just one of 23 states that currently lists post-traumatic stress disorder as a qualifying condition for medical marijuana. Here is a quick list of the states that currently allow medicinal cannabis (in some form) as a treatment for PTSD.

  1. Arizona
  2. Arkansas
  3. California
  4. Connecticut
  5. Delaware
  6. Florida
  7. Hawaii
  8. Illinois
  9. Maine
  10. Maryland
  11. Massachusetts
  12. Michigan
  13. Minnesota
  14. Montana Nevada
  15. New Jersey
  16. New Mexico
  17. North Dakota
  18. Ohio
  19. Oregon
  20. Pennsylvania
  21. Rhode Island
  22. Washington State
  23. Washington, DC

CAMO advocates “using legal oils from industrial hemp” as a holistic treatment for PTSD until real medical marijuana is available.

15 Oct 2017

Surprisingly, 83 y.o. G.O.P. senator Orin Hatch supports cannabis medicinal RESEARCH

This was originally published in “The Rolling Stone” magazine Sept 22, 2017 by Matt Laslo:

Some Utah residents are working overtime to get medical marijuana on the state’s ballot next year. They seem to have just gotten a surprising new Republican ally in their effort – Senator Orrin Hatch.

“There’s no transformation. I’ve always been for any decent medicine,” Hatch replied without hesitation. “I know that medical marijuana can do some things that other medicines can’t. I’m for alleviating pain and helping people with illness.”

Hatch is among a frustrated set of the nation’s policy makers who are up in arms over Washington Post report that Sessions’ Justice Department is blocking the Drug Enforcement Agency (DEA) from approving about two dozen proposals for experts to research the effects of marijuana. Not to legalize weed. Not to sell it. Not even to smoke it. Merely to study it – just as is allowed with deadly and highly addictive opioids, booze and even cigarettes – to find out if 38 states and the District of Columbia have made grave mistakes by allowing marijuana to be used either medicinally or recreationally, or whether those states are actually on to something.

At 83, Hatch agrees with his former Senate colleague Jeff Sessions on much of his prohibitionist stance on weed – but he says the attorney general and his DOJ are basically out of touch when it comes to medicinal marijuana, which can be ingested as an oil or a baked good or even developed into high-grade pharmaceuticals.

“I think it’s a mistake. We ought to do the research,” Hatch continues. “They’re worried about a widespread abuse of the drug, which is something to worry about because it is a gateway drug that’s a very big problem. But there’s a difference between smoking marijuana – using it illegally – and using it to alleviate pain and suffering.”

Pot remains listed by the DEA as a Schedule I drug, which is a classification that by definition means the government sees no medicinal benefit to it, along with the likes of LSD, ecstasy and peyote. But now 30 states have embraced marijuana for a varying degree of medicinal purposes, but there isn’t good, peer reviewed research on it because many researchers don’t want to risk a DEA raid or being cut off from future federal grants.

15 Oct 2017

Dr. Oz surprises Fox News with his view that legalization of cannabis for pain would help with opioid crisis

Oct 15, 2017 “The real story is the hypocrisy around medical marijuana,” Oz said as the Fox & Friends hosts appeared stunned. “People say marijuana is a gateway drug to narcotics; it may be the exit drug to get us out of the narcotic epidemic.  We’re not allowed to study it because it’s a Schedule I drug,” Oz added. “And I personally believe it could help.”

11 Aug 2017

Dr. Jacknin excited to speak on topical hemp and CBD in beauty and skin care at Happi Conference in NJ in November!

 Dr. Jacknin is  excited to be speaking on the endocannabinoid system and topical hemp and CBD in beauty and skin care at the Happi Anti-Aging Conference in New Brunswick, NJ on Nov. 27 and 28. 

This is a cutting edge conference which the top cosmetic and cosmeceutical companies such as J&J, Neutragena, Estee Lauder, attend.  Can hardly wait! 



11 Aug 2017

CBD…What is it??

                        CBD molecule


CBD, which stands for cannabidiol (not cannabinoid), has become the new natural “it thing”. But what is it?

Cannabidiol was first discovered from the hemp plant in 1940 by chemist Roger Adams working at the University of Illinois. In 1963, scientists in Israel figured out its exact chemical structure.  Later research in the 1970s showed that CBD did not cause mental changes like THC,  but was mistakenly thought to be inactive. In the early 1990s the important discovery of the endocannabinoid system renewed interest in numerous phytocannabinoids. Over the past 15 years, hundreds of scientific articles researching how CBD interacts with the human brain and body have been published and the results are amazing!

CBDA, cannabidiolic acid, is the second most common phytocannabinoid produced in the cannabis plant ( the most common being THC). However,  CBDA is the most common phytocannabinoid in hemp, the fiber variety plant. CBDA, found in the raw cannabis flower, is converted to CBD when heated. CBD-rich plants were quite rare in the United States until around 2009, when reports of CBD’s therapeutic value surfaced. Cannabis growers began testing their plants for CBD and made efforts to stabilize CBD-rich varieties. There are now  a number of CBD-rich chemovars such as Charlotte’s Web, AC/DC, Cannatonic, Harlequin, Sour Tsunami, Blue Jay Way, and  others.

CBD Absorption and Metabolism

The bioavailability of CBD after inhalation is moderate, about 31%.  Unfortunately, CBD is absorbed poorly and erratically when taken by mouth. Sublingual absorption rates are low but less variable than oral ingestion. CBD is metabolized in the liver by enzymes in the P450 system. Most of this breakdown product is excreted in feces.

CBD Mechanism of Action

CBD does not bind to the cannabinoid receptor in the same fashion that THC does, which is why it is not intoxicating. CBD changes the way that THC binds to the cannabinoid receptor and blocks the conversion of THC to the more psychoactive 11-hydroxy-THC. CBD.  It also inhibits the reuptake of the endocannabinoid anandamide, thus enhancing the endocannabinoid system. CBD works at numerous non-cannabinoid receptors, such as the 5-HT1A (hydroxytryptamine) serotonin receptor, giving an antidepressant effect. It also works at the TRPV1 (vanilloid) receptor, giving analgesic and anti-inflammatory effects. CBD’s also influences the peroxisome proliferator activated receptors (PPARs) with multiple effects such as anti-proliferation of certain cancer cells, neuroprotection, and cardioprotection. CBD changes the way that GABA, an inhibitory neurotransmitter, binds to the GABA receptor, enhancing the calming, anti-anxiety effects of GABA. CBD also has been shown to reduce drug-seeking behavior and can have therapeutic effects on THC withdrawal and nicotine dependence.

Medicinal Properties of CBD

As you can see, CBD  works at many different places in the body, giving it numerous medicinal properties, which include:

Potent anti-inflammatory
Analgesic (pain reliever)
Anxiolytic (anti-anxiety)
Anti-cancer agent
CBD lessens the intoxicating effects of THC and reduces the adverse effects that some people experience with THC, namely rapid heartbeat, anxiety, and short-term memory loss. At the same time, when CBD is taken with THC to treat pain, the combination reduced pain more significantly than THC alone. In low doses, CBD is described as alerting, in high doses (>300 mg) it can be sedating.  Amazingly, CBD has very little side effects even at high doses.

Hemp CBD vs. Marijuana CBD

CBD is produced in both hemp/fiber variety and drug variety cannabis plants. They are the same compound, but we know from numerous studies that cannabinoids such as CBD work best when other cannabinoids and terpenoids are present, a synergy termed “the entourage effect.”  Hemp is virtually devoid of other cannabinoids and terpenoids. Also, industrial hemp contains very little CBD, necessitating a large number of hemp plants to obtain what can be obtained from one CBD-rich drug variety plant. The use of a large number of hemp plants also increases the risk of toxin contamination as hemp is a bio-accumulator, drawing up toxins from soil. (In fact: industrial hemp was planted around the Chernobyl nuclear power plant after the nuclear explosion in 1986). Most importantly, an excellent study from Israel in 2015 showed that whole-plant CBD, containing cannabinoids and terpenoids, was superior to single molecule CBD, with whole plant extract having a wider therapeutic window and better efficacy at lower doses. Thus, whole plant CBD-rich cannabis is more efficacious than hemp-based single molecule CBD.  

How Should Patients Choose Their CBD?

There are a small number of hemp products on the market that are labeled “hemp” to comply with governmental regulations that require these products to have less than 0.3% THC, but they are robust with cannabinoids and terpenoids. Other products have no cannabinoids including CBD, despite the manufacturers’ claims. In 2015 and 2016, the FDA purchased a number of CBD products online and tested them for the presence of CBD and other cannabinoids, finding that the amount of CBD claimed on the labels was markedly inaccurate — some products did not contain any CBD. In states that have medical cannabis laws, it’s best to obtain products from licensed suppliers who share their test results, which should confirm the product’s robust cannabinoid and terpenoid profiles.  If you are obtaining hemp through online outlets, thorough research is required as there are many false claims are being made.

CBD is truly an astouding compound! There are very few medicines that have such a long list of beneficial properties with little to no side effect and are completely natural. Many patients using CBD as medicine experience life-changing relief of symptoms and are able to discontinue ineffective and toxic medications. Unfortunately, CBD is still classified as a Schedule I federally illegal substance that is still prohibited from being thoroughly researched. We must be free to study this plant’s medicinal benefits to fully understand its impact on human health.

Reference Dr. Bonni Goldstein, https://www.marijuana.com/news/2017/07/know-your-medicine-cbd/