06 Jan 2019

Dr Jacknin interviewed by InStyle.com on Topical CBD

https://www.instyle.com/beauty/cbd-oil-products-beauty-trend-2018

“A study in the Journal of Investigative Dermatology found that the body’s endocannabinoid system is critical to the skin’s basal cells,” Jeanette Jacknin, a board-certified dermatologist specializing in topical cannabinoids in skincare, says. “If you can manipulate the endocannabinoid system, you can extend the life cycle of the basal cells for more radiant, youthful skin.”

The ones that say how many milligrams of CBD are in the product are the best,” says Dr. Jacknin. “Another thing to look at is the back of the ingredient deck. It’s listed from top to bottom in the order of the percentage of ingredients in the product. If you see hemp or cannabis sativa near the top or middle, it has quite a large amount. If you see it near the end of the ingredients, then the brand just put it in there for marketing purposes.”

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06 Jan 2019

Another December interview by Futurederm.com !

My Interview with Jeanette Jacknin, M.D.

What do you tell patients to look for most in skincare — any ingredients or products in particular?

I tell patients to look at the long list of ingredients on the back label and that the ingredients at the top of the list have the highest concentration in the bottle, and the ingredient as the end of list are in very small quantities in the cream. Also, of course, I love hyaluronic acid and jojoba oil for dry skin, tea tree oil for acne, Retin-A for wrinkles, and aloe for sensitive skin.

What do you think are the best in-house dermatological services for patients? What gives the biggest bang for the buck?

I like the results of a good IPL treatment for brown spots, as it is one of the least expensive cosmetic services. Also, in house peels can really make a person’s complexion and appearance much better. Old-fashioned freezing of pre-cancerous sun spots is certainly worth the money to prevent skin cancer.

At what age do you think more invasive cosmetic treatments should be started?

I really don’t see the need before the age of 35 to have laser treatments for facial wrinkles but it depends on sun exposure, where in the country the person lives with intensity and frequency of the sun, history of acne lesions, etc.

What do you feel are the most commonly made mistakes in skincare?

Picking the wrong shade of foundation or powder or sunscreen.

Share your skincare regimen.

I have a ridiculously simple skin care regimen because I am sensitive to most topicals and can’t use most of the great products out there. So I just wash my face with Free and Clear soap and apply natural sunscreen high in zinc and titanium oxide several times a day. When I need a moisturizer in the colder weather I use a hyaluronic acid moisturizer with only a few added ingredients.

Do you have anything else you’d like to add?

Recently I have become very interested in the studies and clinical results which show that topical CBD oil from hemp is anti-inflammatory using many different pathways, and helps with the appearance of aging, dry skin, acne, eczema, psoriasis, and other dermatologic problems. I am particularly impressed with Sopris‘s CBD products.

 

Thank you, Dr. Jacknin! Be sure to visit her website here. Also, receive 20% off Sopris products by following this link or entering the code JJMD at checkout

06 Jan 2019

Dr. Jacknin interviewed for Women in Weed for Centennial Issue

I was happy to be interviewed by Elana Frankel, the editor of the prestigious Women In Weed Magazine:

“Smart Medicine for Your Skin

 The title of Dr. Jeanette Jacknin’s book sparked her understanding of CBD 15 years after it was written. 

In 2001, the book defined integrative dermatology and discussed conventional and holistic treatments for 33 skin conditions. Her belief in combining conventional dermatology with more holistic options as an alternative treatment approach has gained traction over the years. This includes treating the whole person, taking into account psychological and social factors, rather than just physical symptoms, including factors that precede, trigger or exacerbate a condition as well as diet, nutrition and herbal remedies. So, in 2016, when Jacknin tore cartilage in her ankle and a friend suggested CBD for relief instead of traditional pharmaceuticals, it was her medical background and understanding of the confines of current healthcare that led her to study the skin science behind cannabinoids.

CBD, science and skin care

“Hemp oil has great benefits,” says Jacknin. “Even with small amounts of CBD, it is a rich source of omega 3 and 6 fatty acids found in nature as well as vitamins A, B,C,D, and E. Hemp molecules are small and penetrate the skin better than other type of creams and have moisturizing and nutritional properties.” 

So how does it work? The skin has its own endocannabinoid system (“Which is really quite amazing,” notes Jacknin.), helping to regulate the production of various hormones and proteins, including cytokines, which are involved in the immune response, and Caterina-2014 cannabinoid lipids, which regulate sensory, homeostatic and skin inflammation.

Human tissues have at least two types of cannabinoid receptors. CB1 receptors mediate the inhibition of neurotransmitter release (involved with euphoria  found mainly in the brain, but also in the skin), while CB2s modulate cytokine release (usually involved with the anti‐inflammatory qualities mainly found in skin).  A receptor can recognize and bind with molecules, including interactions with phytocannabinoids from cannabis (CBD and THC). The binding affinity of particular cannabinoids to certain types of receptors within the endocannabinoid system have implications in epidermal differentiation (acne and inflammation) and skin development (aging and new cell growth).

 Now what?

There are studies documenting the treatment of acne, eczema, psoriasis and anti-aging but much more is needed. “Expect more in the United States next year,” notes Jacknin. In the meantime, as CBD skincare lines and spa therapies pop up, here are her recommendations.

  1. Look at ingredients. A long list of unpronounceable names is a red flag. If hemp/cbd oil is listed towards the bottom, there is probably hardly any in there. Check the milligram number.
  2. Patch test products before using on the back of your hand or on feet. 
  3. Essential oils are sometimes mixed in to product, so if you have sensitive skin try unscented and be mindful of allergic reactions.
  4. For massage and pain relief, CBD massage oils are a great start but a transdermal product (like a patch) can get under the skin and straight to the muscle. Just be mindful of the adhesive…cheap adhesive can cause a skin reaction.”
06 Jan 2019

Dr. Jacknin interviewed for Domino.com article on CBD for massage

It was a busy December! I was happy to be interviewed by the cutting edge magazine Domino about my thoughts on CBD for massage. Happily and 2018 Farm Bill has since passed and hemp-derived CBD is legal in all 50 states.

You can read it here: 

https://www.domino.com/content/cbd-massage/

Anecdotal evidence and the few-and-far-between studies that have been conducted point towards tension-relief as a key effect CBD can have on muscles—but the benefits don’t end there. An endocannabinoid system in the skin, as board-certified dermatologist Dr. Jeanette Jacknin explains, has receptors for cannabinoids like CBD. When the receptors pair up with cannabinoids, they work to decrease inflammation (like acne, psoriasis, and eczema) through immune pathways.

“A lot of these studies have been in mice,” she explains. “Few have been on humans, because research hasn’t been readily available in the United States because of legislation.” With her background in dermatology and holistic medicine, Dr. Jacknin first gained an interest in studying the superficial skin benefits of CBD when she saw the effectiveness that CBD patches and salves had on her own ankle pain.

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courtesy of Sopris

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The true legality of CBD is the tricky part: it’s made in the U.S. from hemp (a non-psychoactive plant that cannot give consumers a high), but for the past 50 years, U.S. legislation has looped the entire Cannabis genus (including both hemp and marijuana) together as a Schedule I federally controlled substance. If a 2018 farming bill passes, however, hemp could become totally legal and therefore much more available for clinical studies—as well as new product innovation.

It can be tempting, easy even, to denote the effects of CBD on a placebo effect (after all, placebos do work anyway), but Dr. Jacknin stresses that true effectiveness can be seen when you’re using a high-quality product. A massage, when paired with quality CBD, can show instant effects when it comes to muscle relaxation. The topical, inflammation-reducing effects, however, can take some time.

“If the topical is from a great brand that formulates well with other natural analgesics, the relief of pain can be within near-immediate depending on the individual,” she says. “Topical effects for the treatment of skin problems would take longer in terms of days or weeks depending on the individual and the severity of their case. This relates to [the] perception of symptoms—not a cure of anything.”

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28 Nov 2018

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18 Jan 2018

Dietary Hemp Seed OIl for Eczema

There is also evidence to suggest that dietary hemp seed oil can raise levels in the epidermis and make eczematous skin look more like the fatty acid profile found in ‘normal’ skin. In 2005, Dr. J. Callaway, published a study done in Finland in the Journal of Dermatological Treatment documenting the treatment of eczema using hemp seed oil.  Dr. Callaway found that symptoms of skin dryness and itching improved significantly in eczema patients after using hemp seed oil for 20 weeks. Dietary hemp seed oil increased endogenous levels of two essential fatty acids (EFAs), linoleic acid , an omega-6, and a-linolenic acid, an omega-3, as well as boosting levels of linolenic acid (omega-6).  In addition, transepidermal water loss decreased, subjective levels of skin dryness and itchiness improved, and the perceived need for medication among patients was reduced. So hemp seed oil can be used together, internally and externally to help with the symptoms of eczema.

18 Jan 2018

Hemp oil for Eczema

 Hemp seed oil itself has had some success with the symptoms of eczema. As these conditions are characterized by overly dry skin, hemp seed oil can moisturize the skin while avoiding further irritation. In eczema, dry skin occurs due to excessive transepidermal water loss, as persistent inflammation compromises the skin’s ability to act as a barrier.  Hemp seed oil may also provide the key to controlling the imbalance that underlies the condition. Its high concentration of polyunsaturated fatty acids (PUFAs) are believed to reduce itching and inflammation better than moisturizers that are low in PUFAs. Linoleic acid in particular is thought to be particularly effective.